Numerous Holocene volcanic centres (5 stratovolcanoes, including 4 active and potentially dangerous, and 12 monogenetic centres) are discovered within Sredinny Range of Kamchatka. Their exact ages are determined. Spatial and temporal characteristics, as well as composition of Holocene volcanic rocks witness against direct connection of magma genesis with contemporary Pacific plate subduction. Sub-meridional chronological trends and elements of grouping, identified for Holocene volcanic activity of Sredinny Range of Kamchatka, may indicate seismo-geodynamical nature of young volcanic activity and associated with it advection in the extinct island arc system.