Volcanic eruptions from Kamchatka have deposited many unique tephra layers over a large region within the North Pacific, providing important isochrons between key sites such as marine ODP core 883 (Pacific Ocean, Detroit Seamount) and Elgygytgyn Lake (Chukotka, eastern Siberia). Here we present a compilation of C14 dates on major Holocene tephras from the volcanically highly active region, based on decades of detailed stratigraphical fieldwork on Shiveluch, Kliuchevskoy, and other volcanoes.The 12-m thick tephra sequence at the Kliuchevskoy slope has been continuously accumulating during the last ∼11 ka. It contains over 200 visible individual tephra layers and no datable organic material. The section is dominated by dark-gray mafic cinders related to Kliuchevskoy activity. In addition, it contains 30 light-colored thin layers of silicic tephra from distant volcanoes including 11 layers from Shiveluch volcano located only 65 km to the north. We have used EMPA glass analysis to correlate most of the marker tephra layers to their source eruptions dated earlier by C14 (Braitseva et al., 1997; Ponomareva et al., 2007), and in this way linked Kliuchevskoy tephra sequence to sequences at other volcanoes including Shiveluch. The C14 dates and tephras from the northern Kamchatka are then combined into a single Bayesian framework taking into account stratigraphical ordering within and between the sites. This approach has allowed us to enhance the reliability and precision of the estimated ages for the eruptions. Age-depth models are constructed to analyse changes in deposition rates and volcanic activity throughout the Holocene. This detailed chronology of the eruptions serves as a basis for understanding temporal patterns in the eruption sequence and geochemical variations of magmas. This research could prove important for the long-term forecast of eruptions and volcanic hazards.