Distal volcanic tephras in soil sections and lake sediments in the Dvuh-yurtochnoe (Two-Yurts) lake area, central Kamchatka, were investigated in order to provide a chronological framework for the reconstruction of late Quaternary landscape development. Mineralogical and geochemical data point to sources from 5 volcanoes. Ten tephra layers were identified and correlated to known eruptive events. The ages were corroborated by radiocarbon dating of the soil sections around Two-Yurts lake. These findings allow the reconstruction of regional paleoenvironmental change, recorded in the soil sections around Two-Yurts lake. During the Last Glacial Maximum (LGM) time, the area was affected by glacial advances that produced the glacial moraines at the eastern outlet of the lake. A large landslide, ca. 15,000–18,000 14C BP, dammed the valley and led to formation of Two-Yurts lake. Several more landslide events can be recognized in the Holocene, and one affected Two-Yurts lake ca. 3000 14C BP. This event produced a “tsunami”, documented by poorly sorted deposits with rounded pebbles in the onshore sections around the lake. In contrast to the soil sections, tephras buried in the “soupy” lacustrine sediments of Two-Yurts lake are not well preserved and show inconsistent age-depth relationships compared to those suggested by radiocarbon dating, due to sinking through the lake sediments. Nevertheless, tephrochronological data revealed the strong impact of terrestrial landslides on lake sedimentation.