Abstract Data on the geology, petrography, mineralogy, and geochemistry of rocks from Kamen Volcano (Central Kamchatka Depression) are presented and compared with rocks from the neighbouring active volcanoes. The rocks from Kamen and Ploskie Sopky volcanoes differ systematically in major elemental and mineral compositions and could not have been produced from the same primary melts. The compositional trends of Kamen stratovolcano lavas and dikes are clearly distinct from those of Klyuchevskoy lavas in all major and trace element diagrams as well as in mineral composition. However, lavas of the monogenetic cones on the southwestern slope of Kamen Volcano are similar to the moderately high-Mg basalts from Klyuchevskoy and may have been derived from the same primary melts. This means that the monogenetic cones of Kamen Volcano represent the feeding magma for Klyuchevskoy Volcano. Rocks from Kamen stratovolcano and Bezymianny form a common trend on all major element diagrams, indicating their genetic proximity. This suggests that Bezymianny Volcano inherited the feeding magma system of extinct Kamen Volcano. The observed geochemical diversity of rocks from the Klyuchevskaya group of volcanoes can be explained as the result of both gradual depletion over time of the mantle N-MORB-type source due to the intense previous magmatic events in this area, and the addition of distinct fluids to this mantle source.